- University / research
- Country: United States
SAMP1/TMEM201 protects alveolar type 2 cells from DNA damage-associated senescence and restrains pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease in which repetitive injury to the alveolar epithelium and senescence of alveolar type 2 (AT2) cells drive persistent myofibroblast activation and extracellular matrix deposition. Inner nuclear membrane (INM) proteins…