- University / research
- Country: United States
IFNγ-CXCL9-CXCR3 axis links T cell recruitment to skeletal muscle remodelling in human physical frailty
Introduction: Physical frailty is increasingly prevalent in our ageing society, and results in higher morbidity and healthcare costs. Yet, targeted therapeutics are lacking because underlying mechanisms are poorly defined. Human cohort studies have linked inflammation with frailty, but do not…