- University / research
- Country: United States
TACO: An open, interpretable model for microsecond-scale TCR specificity prediction
Predicting antigen-induced T-cell activation from T-cell receptor (TCR) and peptide sequence remains difficult for TCRs and peptides not represented in training data. We present TACO (T-Cell Activation from Chemistry and Orientation), an open statistical model for predicting TCR specificity against…