- University / research
- Country: United States
Cargo levels control endosomal PI(3)P homeostasis through direct feedback between SNX17 and MTM1
The sorting of internalised cell surface proteins through the endosomal network is crucial for cellular function. Phosphatidylinositol-3-phosphate (PI(3)P) is a critical lipid identity cue for organising endosomal sorting but there is limited understanding of how PI(3)P homeostasis is regulated.…