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DEER

2 headlines · 2 outlets · 2026-10-27 → 2026-10-31 · Wikipedia ↗ · 🔒 Follow

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bioRxiv · ☆
  • University / research
  • Country: United States

Unliganded Active State of the β2-Adrenergic Receptor Revealed by Pressure-Resolved DEER and ProGuide Molecular Modeling

The intrinsic ability of G protein-coupled receptors (GPCRs), such as the {beta}2-adrenergic receptor ({beta}2AR), to sample an ensemble of distinct conformational states with varying affinities and catalytic activities for intracellular transducers such as G proteins and {beta} arrestins is a…

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