- University / research
- Country: United States
Interferon-induced OASL restricts ADAR1 p150 RNA binding and A-to-I RNA editing
The interferon (IFN)-inducible RNA editor ADAR1 p150 catalyzes adenosine-to-inosine (A-to-I) editing of host and viral double-stranded RNAs, limiting aberrant innate immune sensing and regulating gene expression. How ADAR1 p150 activity is regulated during host-virus interactions remains poorly…